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TLR4 cell lines
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by Ni(2+). These responses require non-conserved histidines and are, therefore, species-specific.
Date: 11/13/2024
Organized By: Creative Biogene
Web: https://www.creative-biogene.com/genesearch/TLR4.html
Email: contact@creative-biogene.com
Directions: Shirley, NY 11967, USA
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