Forty finalists took home $1.8 million in awards on March 13 at the Regeneron Science Talent Search 2018, the nation’s oldest and most prestigious science and math competition for high school seniors. Science Talent Search alumni have made extraordinary contributions to science and hold more than 100 of the world’s most coveted science and math honors, including the Nobel Prize and the National Medal of Science.

Third place honors and $150,000 went to Isani Singh, 18, of  Cherry Creek High School: Greenwood Village, Aurora, Colorado who worked on "Investigating the Developmental Requirements of Sex Chromosome Genes Affected in Turner Syndrome" towards determining that women with Turner Syndrome (TS), a genetic abnormality in which the second sex chromosome is missing, do have some cells with two X chromosomes.

Knowing that most embryos lacking the second X do not survive, Isani adapted a laboratory protocol to search for and find these normal cells in TS embryos. She also identified genes that are underexpressed in TS, a finding that may help physicians and patients better prepare for the variable medical complications of TS.

The Regeneron Science Talent Search (Regeneron STS), a program of Society for Science & the Public (the Society) is the nation’s most prestigious science research competition for high school seniors.  Since 1942, first in partnership with Westinghouse, then with Intel 1998-2016, and now with Regeneron, the Society has provided a national stage for the country's best and brightest young scientists to present original research to nationally recognized professional scientists.

Learn more about the top ten finalists

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